Salvail appeared as herself in the Robert Altman film Prêt-à-Porter. She also made an appearance in such films as The Fifth Element and Zoolander. She has appeared on the covers of several magazines including ELLE, Marie Claire and Wired.
On the January 9, 2007 episode of the Tyra Banks Show titled "Coming Out Stories", Salvail is said to have come out of the closet.
For some time she was the lead singer in a band called Ten Watt Mary. She has also collaborated with artists such as Bryan Adams and David Zilbert. In more recent years Eve Salvail has become a successful DJ in New York often using the name DJ Evalicious.