Pflug was in the film MASH (1970) as the U.S. Army nurse Lt. Maria "Dish" Schneider. Also, in 1978–79, she played an Army nurse in the second season of the U.S. Navy-submarine-based TV series Operation Petticoat. This series had undergone an almost complete change of cast after its successful first 1977–78 season, and it did not last very long in 1979, when it was canceled.
Pflug's only marriage was to game show host Chuck Woolery. Pflug was Woolery's second wife. The couple married in 1971 and divorced in 1981. Woolery has since married a third time.
Pflug is a graduate of the University of Miami in Coral Gables, Florida. A born-again Christian, she has a daughter, Melissa, with Woolery.