Carradine was born in Hollywood, California, the son of actress Sonia Sorel (née Henius) and actor John Carradine. He is the brother of Christopher and Keith Carradine, paternal half-brother of Bruce and David Carradine and maternal half-brother of Michael Bowen. Carradine has two daughters, one of whom is actress Ever Carradine. He also has a daughter (Marica Reed Carradine) and a son (Ian Alexander Carradine) with his wife Edie Mani. He also has triplets, two girls and a boy, named Patience Dani, Essence Paulia, and Liberty Elder.